There is good reason to limit off-target drug delivery, to minimize side effects in tissues that don't need exposure to the drug.
Is the oral route more effective than topical?
What are the systemic effects of the oral med?
Was the study quoted in the article in any way funded by a pharmaceutical company that would be granted an exclusive license for a "new formulation," or is it trustworthy?
RFK Jr would like to remove scientific scrutiny from the drug approval process, which is the agenda of pharma companies. He's already been successful with this in the med device space using the same argument.
Unfortunately I didn't take any closeups. After some searching I think this was probably xanthoria. It was dry, flakey, and had those fairy cup fruiting bodies. Not so obvious in any of my pics.
Brain-imaging evidence showed that the subjects’ parietal lobes, involved in spatial reasoning, were more active during approximation problems; while the left inferior frontal lobes, involved in verbal reasoning, were more active during exact calculation problems. Studies of patients with brain lesions paint the same picture: those with parietal lesions sometimes can’t decide whether 9 is closer to 10 or to 5, but remember the multiplication table; whereas those with left-hemispheric lesions sometimes can’t decide whether 2+2 is 3 or 4, but know that the answer is closer to 3 than to 9.
I wonder if, in the face of very large numbers, both these systems fail and we default to a social/emotional impression of "powerful/scary."
There is good reason to limit off-target drug delivery, to minimize side effects in tissues that don't need exposure to the drug.