Maybe your HBA is having issues? or a Drive is Failing? have you done a memtest? you may need to do system wide tests, it can even be a PSU failing or a software Bug.
also TrueNAS is built with Docker they use it heavily something like 106 apps, Debian has good ZFS support, but you will end up doing a lot of unneeded work using Debian unless you keep it simple.
up to AMD Ryzen 7XXX and Intel 13xxx Should Work just fine, and at most you may have to use the Debian backport Kernel 6.5 soon to be 6.6, and or pop a new wifi card in it as Dell ships some shitty wifi cards.
I been told it was to big, but if you look at the Linux Kernel, it is huge.
People also love to say Unix, but Linux is not Unix.