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InitialsDiceBearhttps://github.com/dicebear/dicebearhttps://creativecommons.org/publicdomain/zero/1.0/„Initials” (https://github.com/dicebear/dicebear) by „DiceBear”, licensed under „CC0 1.0” (https://creativecommons.org/publicdomain/zero/1.0/)J
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3 yr. ago

  • Also, still can't block communities we've been banned from on the community page. What a joke.

    It would be a nice improvement! Currently you can go to settings -> blocks and you can add a block.

    Voyager let's you block a community by a long press on the community name

  • Molly on GOS, I will see a 5-10m delay on alerts sometimes.

  • The default diet today is highly processed, high carb, low fat, low protein... so any change would be a improvement.

    As we have seen in the metabolic psychically papers, lots of people would see near immediate benefits in mood.

    Selfishly a carnivore world would give better options at restaurants!

    Of course, many people 'live to eat', and transitioning to 'eat to live' would be profound... fast food and restaurants would see a fairly big dip in sales, but they would adjust.

    I'm not ready to give up on my coffee yet.

  • Cows eat grass. Humans use more calories digesting grass than they gain from eating grass, so cows are infinitely more efficient than humans at gaining calories from grass.

    And there are places in the world where growing human food would destroy the land. Semi-deserts like Texas and Montana. Grazing cattle there is a good idea. Bison would be even better because the native prairie there is adapted to bison, but cattle are a close substitute.

  • Papercut

  • Drenick et al. demonstrated that, after a 2-month fast in obese subjects, insulin stimulation failed to precipitate hypoglycemic reactions with plasma glucose as low as 9 mg/dl (0.5 mM) [25].

    This is really important, when fully fat adapted the human body can exist with massively low blood glucose levels. Well beyond what would be considered a hypoglycemic emergency. This isn't relevant for people just doing ketosis for general health, but it is illustrative of the power of fat adaption. This paper calls it out because its part of a cancer treatment protocol where they create hypoglycemic states in patients.

    During prolonged fasting, blood glucose levels below 30 mg/dL (1.70 mM) have been sustained continuously for several months without adverse effects [22, 23].

  • Ahh! let's talk about ought!

    Since humans store fat, one could see mechanistically we are setup to run on the energy we store: fat

    When humans go more then 4 hours without eating glucose (skipping a meal, keto, fasting, or sleeping) they are running on fat, including the brain. If you want to prevent your brain from using fat you need to drip feed glucose all day (which some people try really hard to do), but when you sleep some of that fat will finally get to be used by the brain. One could reasonably argue the default energy of the human body is fat, hence why it's used during sleep.

    https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2016.00053/full#h7

    Both short-term PET and arterio-venous difference studies in humans show that brain glucose consumption decreases as ketone availability to the brain increases. These results suggest that ketones are actually the preferred energy substrate for the brain because they enter the brain in proportion to their plasma concentration irrespective of glucose availability; if the energy needs of the brain are being increasingly met by ketones, glucose uptake decreases accordingly. This decrease in brain glucose uptake when both ketones and glucose are available supports the notion that ketones are the brain’s preferred fuel.

    The body will use glucose when available, because glucose is so damaging to cells - glycation happens rapidly. As soon as any glucose elevations are seen in the blood stream insulin is immediately released to push glucose into fat cells and get blood glucose levels back to the low normal.

    However, I'm open to being wrong: Why 'ought' the brain use glucose instead of fat?

  • 9m27s:

  • french toast!

  • Sure, humans are lipvores we store fat we run on fat, stored fat is often seen as weight.

    Regardless if a person is skinny, fat, or in between their brain can run on fat.

  • 1h:02m -

  • The talk about WWII women gaining fat while their families were starving was heart breaking (around the 32m mark)

  • I'm not talking about your weight, I'm talking about the fuel source for the brain. The body runs on fat, the brain runs on fat. It can, when available, also use glucose - but the entire metabolic system tries to keep glucose levels low and consistent rather then spiked and high.

  • I did some poking into Dr Glandt's publication history:

    • 2025 — Myths and Facts Regarding Low-Carbohydrate Diets. Summary: review/opinion paper addressing common claims about low-carbohydrate and ketogenic diets. DOI: https://doi.org/10.3390/nu17061047

    • 2024 — Use of a very low carbohydrate diet for prediabetes and type 2 diabetes: An audit. Summary: clinical audit of a very-low-carbohydrate ketogenic program for prediabetes and type 2 diabetes. DOI: https://doi.org/10.4102/jmh.v7i1.87

  • Starches and carbs feed the brain.

    Turns into blood glucose, which the body can use in the brain, but works as hard as it possibly can to put into fat cells. The brain also runs perfectly well on fat, humans store fat not glucose for long term energy.

  • We are getting closer to optical computers!

  • You need to be relatively healthy to do full range calisthenics. For people starting off at a deficit then weight training allows immediate muscle targeting while someone gets back into healthy range

  • If a single organization controls it but the architecture is over a large area then it's distributed.

    Would you say someone who uses cloud flare is using a decentralized architecture?

  • Friendly Carnivore @discuss.online

    Meat Buying Guide - Butcher Wizard

  • Friendly Carnivore @discuss.online

    484lbs/220kg Gamer does carnivore for 2 years

  • Media Reviews @hackertalks.com

    Station Eleven - 2021 - Series

    en.wikipedia.org /wiki/Station_Eleven_(miniseries)
  • Media Reviews @hackertalks.com

    Way of the Dragon - 1972

    en.wikipedia.org /wiki/The_Way_of_the_Dragon
  • jet's interesting finds @hackertalks.com

    Hormuz Disruptions, US Navy Escort Plans (or lack of) and Impact on Global Trade | 10 March 2026 - WGWS

  • Metabolic Health @discuss.online

    Why Alzheimer’s May Be a Metabolic Disease with Dr. Bikman

  • Low Carb High Fat - Ketogenic @discuss.online

    Metabolic Management of Glioblastoma - Thomas Seyfried

  • Media Reviews @hackertalks.com

    Andromeda Strain - 1971 Film

    en.wikipedia.org /wiki/The_Andromeda_Strain_(film)
  • Media Reviews @hackertalks.com

    The Cuckoo (film) 2002

    en.wikipedia.org /wiki/The_Cuckoo_(film)
  • Low Carb High Fat - Ketogenic @discuss.online

    The Awkward Question Every Patient Should Ask Their Doctor - MD Mason

  • Friendly Carnivore @discuss.online

    Catching up on my reading today

  • Friendly Carnivore @discuss.online

    An Epidemiologist's perspective on nutrition and network meta analysis NMA - Dr. Thornley

  • Friendly Carnivore @discuss.online

    Sacred Cow - Documentary - 1h30m

  • Low Carb High Fat - Ketogenic @discuss.online

    Cancer as Mitochondrial dysfunction - Dr. Seyfried Interview

  • jet's interesting finds @hackertalks.com

    finetune macos audio router and mixer; open source, great for mixers!

  • jet's interesting finds @hackertalks.com

    Awesome Arma Helicopter setup tour by GnarSasquatch

  • Friendly Carnivore @discuss.online

    Reading Literature with Bart Kay - SD, SE, Significance

  • Friendly Carnivore @discuss.online

    Why MD Chaffee never eats carbs

  • Low Carb High Fat - Ketogenic @discuss.online

    Can Keto Help Serious Mental Illness?

  • Friendly Carnivore @discuss.online

    How EVERY* Milk Product Is Made