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3 yr. ago

  • There was a study on the efficacy of paracetamol with ibuprofen compared to morphine and it was a very close thing, within the margin of error. The combination of paracetamol and ibuprofen works on pain in two different ways at the same time, whereas opiates only work in one major way. It seems overall more effective in many cases.

    That said, some people report that morphine doesn't remove their pain as much as it removes their caring about it. It reduces the salience and therefore makes them respond less. I don't know from experience given the lack of response, but maybe that is part of why it is so addictive, you don't have to care any more about pain or other issues.

  • Yeah, I agree with your thoughts on the 95% thing. Its like with pain management. I am completely non responsive to morphine. Most people respond well, it just feels cold in my arm and that's it. When I flayed my wrist they gave me tonnes of morphine, the maximum dose I could have, and I had almost no effect at all. I got more from the paracetamol they gave me after that which was good because they had to remove my temporary dressing from a very large open wound and any relief was helpful. Now I just ask for aspirin and paracetamol, though after a wonderfully fun heart infection I can't use aspirin for pain relief without considerable bleed risk. Oh well, paracetamol it is.

    But yes, if I go in for emergency care and tell them "no morphine, paracetamol only" they will probably not take it seriously without a doctor supporting it. Good thing I have a fairly high pain threshold.

  • I come back time and again to the difference between reasonable and recommended. A recommendation in medicine is something you would be unwise to ignore as a doctor. Reasonable is something that you as a patient should do. A doctor is going to tell you all the recommended things because the way medicine works is all around what is shown to a reasonable statistical level to be a good idea, or at least seems that way. They will still recommend some things that are nonsense and they will still make mistakes, but they won't be sued.

    If you try something and that works for you then you have a sample of one. It may have done nothing and the problem resolved itself, it may have solved the problem, it may even have slowed your recovery, but if you have the same problem again it is fairly reasonable to do the same thing that seemed to work last time. It isn't proof, but it is reasonable to try again.

    Does having a kebab on the way home from a night of drinking actually prevent hangovers? Well, maybe, it does have salt and that is depleted during drinking, but is a doctor ever going to recommend that? No, never.

  • I got a lot of fiddling with things when I was a kid so all my fidget toys that I found for myself got taken away in the places I needed them most like school etc. My solution was to use my own hands. I curl my fingers a little and then touch the crease between the first and second metacarpal on the index finger, then go down to middle and ring in the same spot, then diagonal up to the flat of the second metacarpal then the crease of the second and third metacarpal, then I reverse course. I can do the same with the straight from the second to third metacarpal crease on index, middle, then ring, then diagonal up to the first to second crease on the index. It is a nice pattern and except for times where I have broken or flayed my hands respectively it is always available. I can go slow or fast, do variations of the patterns, and I can do it subtly so people don't notice. Very... Handy. Ha.

  • I hated the above Avatar movie but I loved TLoK. She is such an awesome character and has tonnes of growth and development, along with the fantastic lgbt end of the series. It was definitely a little difficult in the first few episodes but a big part of that was the transition from a rural setting to a city setting decades later, so it went from the backwater technology level to the cutting edge near a century later.

  • Motivated

  • Something to consider is differences in absorption and context. One angle is coabsorbtion, where two molecules can be absorbed better together than apart. Another is binding, such as with lectins which can bind to some micro nutrients and prevent absorption. So if you add lots of something which is not bound like it naturally would be with foods that contain it then absorption may be disregulated and you may have wildly different levels absorbed than the nutritional label would suggest.

    Adding lots of vitamin C to foods because of a cosmetic or preservative function may not be the best idea given how active it is in the body. Maybe it has a similar effect in the gut to what it does in the food in the packet, killing a bunch of microbes, and therefore could impact our gut microbiome. We don't have the data yet on the mechanisms, so we should withhold judgement for now.

  • I've been relistening to the Jumper series by Steven Gould, it is fun and interesting to see how something written not all that long ago is from a totally different world. The way technology worked in the 90s is so different to how it works now and many of the problems in a science fiction book with teleportation can be solved by a mobile phone.

    Also, I just finished the Murderbot series given the release of the newest book, the Bobiverse series, and the Children of Time series with the latest installment Children of Strife.

    I also have a massive fanfic called The Winter Of Widows which is based in Westeros from A Game Of Thrones. It is really fun and interesting and the writing is honestly fantastic. Definitely publishable level of writing skill. It is based on the idea of a modern person with some knowledge of things like four field crop rotation and coplanting going into that medieval world and making things work as much as possible. Very cool, very fun.

  • It isn't one place. Neurotypical eye movement is fairly constant, with a lot of time spent looking at or around other people. People who are autistic or have ADHD have a different pattern and often get commentary that they are staring at something like they want to burn it down or that they are off with the fairies.

    To help with masking one strategy is to have a frequent face check, looking near the faces of people who are in the room, especially those who have just entered or moved. If someone is speaking they should be looked at but not 100% of the time, more like 70-90%. Other time should be spent looking around the room, looking at whatever is behind or around them, or at whatever they are presenting if applicable.

    That said, if that isn't enough clarity I would recommend spending some time actually watching other people. You can do this in a classroom environment but people may find it disconcerting, so using sunglasses and doing it at a café is a fairly good option. Pay attention to where their eyes are going and what they are doing. If they are talking to someone compare their eye behaviour while they are talking to while they are listening, it is quite different. Same with if they are eating, drinking, reading, and so on. Some people spend a surprisingly large portion of the time while reading not looking at the page.

  • Yep, I have a strong reduction in the ongoing stress which keeps me awake. If I want to have a nap in the day I take my stimulants before it and I can actually sleep, otherwise not a chance.

  • Others have already pointed to resources, so I will point to an approach instead. You should start by figuring out why you want to learn Italian and really codify those reasons for yourself. Keep those reasons in mind for the next step.

    What Italian do you want to learn? Academic? Soap opera? Opera style? Casual conversation with Italian relatives? These all define a different set of Italian language to focus on and different resources to use.

    For example, if you just love opera and really want to experience it in the original language you will likely need to learn an older form of Italian, more for the time the operas were written. That means modern TV Italian may mislead you and give you "bad habits"of modern speech that will make understanding operas harder.

    That said, if you want to speak to relatives in Italy then the modern language from TV is probably good enough and that resource will be very useful for you.

    So once you know which language register you are targeting you can then think about what sources of that language in use you can gain access to. Getting language lesson recordings is something some people find useful, but it is very scripted and rarely actually shows you the language in use naturally, it is very scripted and overly structured.

    If you decide you want to be able to speak like a native then the best recommendation I can give is to learn like kids learn. Watch kids shows, listen to the kind of speech kids would hear, and produce your own child speech when you are up to it. Be wrong, make mistakes, and get corrected. Use the language to communicate simple ideas first then expand slowly to more complex ideas. Kids don't understand tense and status, they string things together and get the conjugations wrong and people correct them. They also listen, a lot. Like, an insane amount. Match them.

    Once you listen a lot and read a lot in Italian the production will get more natural and native like and the rules can help clarify things, but over saturating yourself in grammar and the like can actually hurt your native level acquisition. Remember that in English you don't think about irregular conjugations of the verb run, you just say run and ran. When you were a kid you probably said "He runned" and people corrected you, so now it feels natural. That is what you want.

    As for specific resources, I would recommend looking for Italian sources of ongoing media, for example if you want current culture language look for TV shows and movies that are Italian native, coming from inside their culture. You want the language and the culture together because that is how they exist. Saying you understand Spanish because you know a siesta is a nap is not really correct, and in the same way the fact that lunch is very different in Italy will make a direct translation without cultural context very odd seeming to native speakers.

    So broadly, think about what you want, find resources that align with that eventual goal, start as a kid, learn alongside the culture, and make lots and lots of mistakes.

  • OK, so no shade on your idea, but you actually can tell your dog he is OK.

    Using a loud voice is a good indication that there is a threat or play, one of the two. Using a super quiet voice, such as a whisper, can convey the opposite. I have worked with a bunch of dogs and the most effective thing I have found for reducing barking and panic is to whisper their name with a positive tone and get down low enough for cuddles and petting.

    They tend to look at me confused, tilt their head, then eventually stop barking and come over. I then give them quiet praise and lots of petting and cuddles as per their preference. Over a fairly short time they tend to shift to a short set of barks to announce the threat followed by coming to me to seemingly verify my attention to the issue, then they settle down.

    This is mostly with either family dogs, 5 of those, or client's dogs, another bunch to varying degrees.

    Also, I would recommend Training Levels: Steps to Success by Sue Ailsby. I have used that book for a lot of dog and cat training and honestly it also works with how I interact with kids. Clear communication, lots of praise and love, capturing behaviours and associating them with words, and never ever using negative stimuli like hitting or yelling. Or as I see it now, respect. Dogs are intelligent beings and if you try to find your common communication tools you can be much more effective at sharing your needs and getting their buy in. Same with kids, actually listening to their needs and observing their behaviour gives you a massive step up, and then never ever being mean or unsafe and always being safe and protective can take you a long way.

  • Ah, good to know. I have found that the state I was used to calling tired was actually really exhausted, absolutely out of energy. Using Ritalin made the cost of things much lower so I felt like I could go for hours after my dose ran out. It was actually that I had gotten used to being absolutely ruined by the day and expected to feel like crap that drove my response, and now I go to bed with the capacity for a fair bit more than I used to.

    I go to bed less fatigued and tired and sleep more than I did before Ritalin, but I do sometimes have trouble sleeping. I have found that heavy work, like a weight lifting routine or playing with kids, helps a lot with getting the physical agitation under control. I need to be active to be OK and when I am not able to be active I end up with depressive symptoms and sleep disturbance.

    I would recommend trying a calisthenics or weights routine at some point, maybe a few months down the line, to see if it helps after your initial adjustment. It also helps with getting mood regulation working a bit better and can make sitting still much easier. I have worked various jobs and lifting heavy things helped a lot with the physical symptoms, though the boredom set in and made the job intolerable fairly quickly. I now work in personal disability care and the varied needs of my clients helps to make the job sustainable over a longer time.

  • Do you mean you didn't sleep the night after you had a dose in the morning? Normally the dose wears off after 3-4 hours for standard release Ritalin and 6-7 hours for extended release. That would mean if you took it at 10am it should be completely worn off around 2pm for standard Ritalin and by 5pm for extended release. Did you take a second dose?

    It is important to remember that how it is today is unlikely to be how it is in a few months. Your body has to get used to processing Ritalin and also the different level of demand you will place on it given your improved capacity. You may overextend yourself and maybe even hurt yourself in this process. It is normal to have some trouble adjusting and small issues like one missed night of sleep but it should level out within a fairly short time, maybe a week or two. If you have ongoing disruption make sure to talk to your prescribing doctor and make sure it isn't a side effect.

    Good luck, have fun!

  • My personal recommendation is to get started asap with what you have. That would mean using any old thing you have laying around. Do you have an old laptop? They are ideal for beginner self hosting as you can physically access the machine and it includes a battery backup right in the machine. Usually they are also fairly lower efficient, so that is nice too.

    Buying dedicated hardware acts as a barrier to actually doing things, so getting past that is key. If you find you don't actually want to do self hosting you can just stop using your old laptop, but if you bought a full server machine it will be a bit of a trap and make you feel like you failed in some way. Also, the cost right now is fairly prohibitive, but using existing hardware can make that much more manageable.

    As for what to run, I would recommend trying a fresh install of a distro based on Debian, Ubuntu, Fedora, and Arch. Yes, four. They are different and have a different feel to them, but also have different communities. By going through the process of installing each one you will get a feel for the system and the community around it and have a better idea what works for you. I spent a few years having around the Debian end of things but eventually moved over to Arch stuff and am currently using EndeavourOS. Your experience will likely be different to mine but trying a few different options will help you figure it out.

    Then moving on to services. Try to see what you actually use your machine to do now and then find services for that. For example, if you use something like Google Drive to synchronise data from your phone to your desktop then try using Syncthing to replace that. If you use Netflix to watch stuff try using Jellyfin. If you do play things like Minecraft get a local server running.

    These will all be for learning, so their performance doesn't need to be better than what a professional can provide, they just need to work and be yours to learn with. If you find you love doing this and enjoy the process but the hardware is holding you back this is a good time to upgrade to a dedicated machine.

    For this I would recommend getting an office computer like an Optiplex or similar, just a basic office computer with an i5 or similar. You will want a fairly good amount of RAM in it, probably 16GB minimum and really 32GB is where things start getting good. A dedicated graphics card is not likely to be useful this early as the iGPU in most modern processors is actually fairly robust and should handle transcoding video for most use cases at a small scale. Storage could be one SSD for the OS and multiple spinning disk drives in a RAID or similar configuration for storage. The SSD will make the actual OS faster, decrease boot times, and make it faster to install and update things making updates less disruptive. The spinning media is way cheaper and you can backup all of your OS drive onto the spinning disks as a cron job in low usage times.

    That's my two cents on it, start with what you have, expand as you need but not aggressively before you need it, and try things now before you are too afraid to mess something up because you rely on it. Remember to have fun and experiment, nothing teaches better than experience. Enjoy yourself, don't take it too seriously, and don't lock yourself in to one specific thing, be flexible and willing to experiment.

  • My experience may be different to yours, but I found that I could actually sleep better with Ritalin on board than without. I can actually have a nap if I decide to and will actually fall asleep while having an active dose, whereas if I don't I am too agitated and can't relax enough for a nap.

    As for eating, OMAD (One Meal A Day) is good for me, I can not worry about it and just eat in the evening and cover my full day intake in one go. It makes organisation much easier simplifies my schedule. It is also better for blood sugar regulation and insulin resistance, so if you are prediabetic it can help reverse that damage.

    That said, if you take it every day you will probably find your hunger signal changes to be more obvious while on the meds. I have found that I can get my three meals a day while on Ritalin after a couple of years of taking it, but skipping is also fine and doesn't upset me like it does without meds. This is also true of pain, I can tolerate pain much better with my meds than without. The pain isn't gone, it just doesn't intrude and disrupt as much so I can keep doing other things.

    I will also say that the sense of holding two tasks and switching between them, not forgetting the other, is something that I find works better off the meds than it did before the meds. I assume it is because I can actually train the skill with the meds on board and get better at it, then when I am off the meds the pathways are stronger and easier to use. I can't say that for sure, but it certainly seems more possible to ignore distractions off the meds than it was before the meds, so I think skill is a part of it, though the other side is probably some degree of burnout and a lack of resources before the meds compared to after having them for a while.

    Anyway, good luck, I hope it goes well for you.

  • As an autistic person with ADHD too I was going to say this. I hate my name being used, I strongly prefer dude or mate, I'll even take "hey you", but using my name is very similar to extreme eye contact or touching my hands. No, no thank you, I would prefer not to.

  • One can dream, but action is better. Asking for transparency is a good start, having legislation presented before voting for public comment is actually not that hard an ask for a legislature. Starting at your most local level and asking them to put legislation under consideration publicly on the local governmental site is a reasonable ask and may actually be done in a reasonable timeframe. Asking the next level up for the same once it is done locally and works out fine is actusy easier than starting at that level, so starting smaller is practically more effective.

    I would recommend asking your most local form of government for the transparency you want and explaining your reasoning. Go to town hall meetings, be part of the process. It is more possible at that local level than at any higher level.