I bought an Orange Pi 5 earlier this year to replace an old RPi 4. I runs various docker containers plus some custom tools I wrote myself in .NET and rust. Yes, .NET on a random ARM SBC. No issues.
Honestly the only downside was the case availability, at the time there was only a choice of two cases and neither looked as good as the Flirc case for the RPi 4.
I know this is a harmless "what if" but let's be encouraging people to explore more languages not to choose a single one to be everything for all time.